BitterDB id=1340 Detailed experimental validation described in the associated resource.
References for the compound bitterness
Resource
Comment
[1]
Lei W. et al. Functional Analyses of Bitter Taste Receptors in Domestic Cats (Felis catus), PLOS ONE, 2015, 10(10) PubMed 26488302
[2]
Kim D. et al. Identification and Characterization of Novel Bronchodilator Agonists Acting at Human Airway Smooth Muscle Cell TAS2R5, ACS Pharmacology & Translational Science, 2020, 3 (6), 1069-1075 PubMed 33344890
[3]
Behrens M. et al. At the Root of T2R Gene Evolution: Recognition Profiles of Coelacanth and Zebrafish Bitter Receptors, Genome Biology and Evolution, 2021, 13(1) PubMed 33355666
[4]
Jiao H. et al. Local Adaptation of Bitter Taste and Ecological Speciation in a Wild Mammal, Molecular Biology and Evolution, 2021, 38(10), 4562–4572 PubMed 34240186
[5]
Cui M. et al. Activation of specific bitter taste receptors by olive oil phenolics and secoiridoids, Sci Rep, 2021, 11, 22340 PubMed 34785711
[6]
Gibbs M. et al. Bitter taste sensitivity in domestic dogs (Canis familiaris) and its relevance to bitter deterrents of ingestion, PLOS ONE, 2022, 17(11) PubMed 36449493
hTas2r5
fcTas2r2
cfTas2r1
dreTas2r3a
sgTas2r119