Bergapten help

BitterDB id=1224 , Natural
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] URL link
[2] Mancuso G. et al. Phytochemicals from Ruta graveolens Activate TAS2R Bitter Taste Receptors and TRP Channels Involved in Gustation and Nociception, Molecules, 2015, 20(10), 18907-18922 PubMed 26501253
[3] Yan J. and Tong H. An overview of bitter compounds in foodstuffs: Classifications, evaluation methods for sensory contribution, separation and identification techniques, and mechanism of bitter taste transduction, Comprehensive Reviews in Food Science and Food Safety, 2023, 22(1), PubMed 36382875
[4] Mancuso G, Borgonovo G, Scaglioni L, Bassoli A (2015). Phytochemicals from Ruta graveolens Activate TAS2R Bitter Taste Receptors and TRP Channels Involved in Gustation and Nociception. Molecules 20(10): 18907-22. PubMed 26501253

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r10 2.8 PubMed:26501253

Sensory data about the compound bitterness: help

Sensory Data Type Value Reference
Bitter recognition threshold 0.0180000 [mM] Reference

Properties: help

216.1900 [g/mol] 2.54780
0 4
3 3
1

Identifiers: help

484-20-8
C12H8O4
BGEBZHIAGXMEMV-UHFFFAOYSA-N

Links:

[1] 2355
[2] ZINC00057731