BitterDB ID=1181

Magnesium chloride

BitterDB id=1181
Detailed experimental validation described in the associated resource.

References for the compound bitterness

	Resource	Comment
[1]	URL link
[2]	URL link
[3]	Behrens M. et al. The human bitter taste receptor TAS2R7 facilitates the detection of bitter salts, Biochemical and Biophysical Research Communications, 2019, Volume 512, Issue 4, Pages 877-881 PubMed 30928101
[4]	Delompre T. et al. Taste Perception of Nutrients Found in Nutritional Supplements: A Review, Nutrients, 2019, 11(9), 2050 PubMed 31480669
[5]	Ziegler F. and Behrens M. Bitter taste receptors of the common vampire bat are functional and show conserved responses to metal ions in vitro, Proceedings of the Royal Society B: Biological Sciences, 2021, 288(1947) PubMed 33784867
[6]	Susan S. S. et al. The effect of sweeteners on bitter taste in young and elderly subjects, Brain Research Bulletin, 1994, 35, 3, 189-204 PubMed 7812797

Known bitter receptors targets:

Receptor Name	Effective concentration (μM)	EC50 (μM)	References
hTas2r7		10000.0	PubMed:30928101
hTas2r7	30000.0		PubMed:31066447
droTas2r7	100000.0		PubMed:33784867

Sensory data about the compound bitterness:

Sensory Data Type	Value	Reference
Bitter recognition threshold	15.0 [mM]	Reference
Bitter recognition threshold	100.0 [mM]	Reference

Properties:

Mol. Weight: 95.2100 [g/mol]	AlogP(octanol-water): -6.37280
# Hydrogen Bond Donor: 0	# Hydrogen Bond Acceptor: 0
# Aromatic Rings: 0	# Rings: 0
# Rotatable Bonds: 0

Identifiers:

CAS Registry Number: 14989-29-8,7786-30-3

Formula: Cl2Mg

IUPAC Systematic Name:

SMILES:

Canonical SMILES:

InChI Key: TWRXJAOTZQYOKJ-UHFFFAOYSA-L

Links:

[1]

PubChem