Amygdalin, D-Amygdalin help

BitterDB id=102 , Natural
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, et al. (2010). The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35(2): 157-70. PubMed 20022913
[2] URL link
[3] Imai H. et al. Functional diversity of bitter taste receptor TAS2R16 in primates, Biology Letters, 2012, 8(4) PubMed 22399783
[4] Jiao H. et al. Local Adaptation of Bitter Taste and Ecological Speciation in a Wild Mammal, Molecular Biology and Evolution, 2021, 38(10), 4562–4572 PubMed 34240186
[5] Lang T. et al. Activation Profile of TAS2R2, the 26th Human Bitter Taste Receptor, Molecular Nutrition & Food Research, 2023, 67(11) PubMed 36929150
[6] Karolkowski A. et al. Non-Volatile Compounds Involved in Bitterness and Astringency of Pulses: A Review, Molecules, 2023, 28(8), 3298 PubMed 37110532
[7] URL link

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References Sequence variant
Human  hTas2r16 3200.0 PubMed:20022913 AAH95524.1
Human  hTas2r16 2300.0 20000.0 PubMed:37110532
Frog  lcateTas2r143 10000.0 PubMed:36780530
Blind Mole Rat  sgTas2r118 10000.0 PubMed:34240186
Blind Mole Rat  sgTas2r143 10000.0 PubMed:34240186

Sensory data about the compound bitterness: help

There is no sensory data available

Properties: help

457.4300 [g/mol] -3.10802
7 12
1 3
7
457 [mg/kg B.W.]

Identifiers: help

29883-15-6,51371-34-7
C20H27NO11
XUCIJNAGGSZNQT-JHSLDZJXSA-N

Links:

[1] 656516
[2] ZINC000008214484