Famotidine help

BitterDB id=101 , Synthetic
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, et al. (2010). The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35(2): 157-70. PubMed 20022913
[2] Lang T. et al. Activation Profile of TAS2R2, the 26th Human Bitter Taste Receptor, Molecular Nutrition & Food Research, 2023, 67(11) PubMed 36929150
[3] Behrens M. et al. A singular shark bitter taste receptor provides insights into the evolution of bitter taste perception, Proceedings of the National Academy of Sciences, 2023, 120(48) PubMed 37956436

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r10 300 PubMed:20022913
Human  hTas2r44 300 PubMed:20022913
Mouse  mTas2r121 30 50 PubMed:27226572
Shark  scTas2r1 300.0 PubMed:37956436
Shark  cplTas2r1 300.0 PubMed:37956436

Sensory data about the compound bitterness: help

There is no sensory data available

Properties: help

337.4600 [g/mol] -0.76800
4 6
1 1
7

Identifiers: help

698387-09-6,76824-35-6
C8H15N7O2S3
XUFQPHANEAPEMJ-UHFFFAOYSA-N

Links:

[1] 5702160
[2] ZINC000001530636
[3] DB00927
[4] 7074