BitterDB

hTAS2R48 - Human (Homo sapiens) Taste Receptor Type 2 Member 48

Alternative Names: Taste receptor type 2 member 23 T2R23 , Taste receptor type 2 member 19 T2R19

Links and Citations:

UniProt	P59542
GPCRDB	t2r19_human
GeneCards	TAS2R19
The Human Protein Atlas	ENSG00000212124-TAS2R19
IUPHAR/BPS	link

Properties

Organism: Human
Location: chr12:11,174,272-11,175,170 UCSC
Number of known ligands:
MW: 33,908 (Da)
Sequence:

MMCFLLIISSILVVFAFVLGNVANGFIALVNVIDWVNTRK ISSAEQILTALVVSRIGLLWVMLFLWYATVFNSALYGLEV RIVASNAWAVTNHFSMWLAASLSIFCLLKIANFSNLISLH LKKRIKSVVLVILLGPLVFLICNLAVITMDERVWTKEYEG NVTWKIKLRNAIHLSSLTVTTLANLIPFTLSLICFLLLIC SLCKHLKKMRLHSKGSQDPSTKVHIKALQTVTSFLMLFAI YFLCIITSTWNLRTQQSKLVLLLCQTVAIMYPSFHSFILI MGSRKLKQTFLSVLWQMTR

Known Ligands

No ligand has been identified.

Experimental/ Computational 3D structures

Here are links to the 3D structures of the receptors. If an experimental structure is available, it is recommended to use the RCSB PDB link. Otherwise, you can use the computationally predicted AlphaFold 3D model.

RCSB PDB: link

AlphaFold: link

Protein Diagram

When using this 2D protein diagram,please cite us:
Ayana Wiener; Marina Shudler; Anat Levit; Masha Y. Niv. BitterDB: a database of bitter compounds. Nucleic Acids Res 2012, 40(Database issue):D413-419.
Click here to view the paper: BitterDB paper

SNPs Table

Receptor	Location	BW number	Residue	MAF	dbSNP
TAS2R48			R299C	0.3498	rs10772420

Known Mutations Table

No mutations were reported yet.

Known SNP Table

Receptor	Location	BW number	Residue	MAF	dbSNP
hTAS2R48		0.00	K126Q	0.0000	rs12424373
hTAS2R48		0.00	R299C	0.3498	rs10772420