BitterDB

hTAS2R42 - Human (Homo sapiens) Taste Receptor Type 2 Member 42 help

Links and Citations:

Q7RTR8
t2r42_human
TAS2R42
ENSG00000186136-TAS2R42
link

Properties help

  • Human
  • chr12:11,338,599-11,339,543 UCSC
  • 1
  • 36,195 (Da)


  • MATELDKIFLILAIAEFIISMLGNVFIGLVNCSEGIKNQK VFSADFILTCLAISTIGQLLVILFDSFLVGLASHLYTTYR LGKTVIMLWHMTNHLTTWLATCLSIFYFFKIAHFPHSLFL WLRWRMNGMIVMLLILSLFLLIFDSLVLEIFIDISLNIID KSNLTLYLDESKTLYDKLSILKTLLSLTSFIPFSLFLTSL LFLFLSLVRHTRNLKLSSLGSRDSSTEAHRRAMKMVMSFL FLFIVHFFSLQVANWIFFMLWNNKCIKFVMLALNAFPSCH SFILILGNSKLQQTAVRLLWHLRNYTKTPNPLPL

Known Ligands help

Download SDF file of selected compounds.

Experimental/ Computational 3D structures help

Here are links to the 3D structures of the receptors. If an experimental structure is available, it is recommended to use the RCSB PDB link. Otherwise, you can use the computationally predicted AlphaFold 3D model.

link

link

Protein Diagram help

Receptor snake diagram

When using this 2D protein diagram,please cite us:
Ayana Wiener; Marina Shudler; Anat Levit; Masha Y. Niv. BitterDB: a database of bitter compounds. Nucleic Acids Res 2012, 40(Database issue):D413-419.
Click here to view the paper: BitterDB paper

SNPs Table help

ReceptorLocationBW numberResidueMAFdbSNP
TAS2R42EC2 Y175F0.4593rs35969491
TAS2R425.54S196F0.4593rs5020531
TAS2R42EC3 G255W0.2392rs1669413
TAS2R42EC3 Y265C0.22rs1451772
TAS2R42R292Q0.22rs1669412
TAS2R42N310K0.2392rs1669411
TAS2R42A311P0.2392rs1650017

Known Mutations Table help

No mutations were reported yet.

Known SNP Table help

ReceptorLocation BW number Residue MAFdbSNP
hTAS2R420.00A311P0.2392rs1650017
hTAS2R42EC3 0.00G255W0.2392rs1669413
hTAS2R420.00N310K0.2392rs1669411
hTAS2R420.00R292Q0.2200rs1669412
hTAS2R425.54S196F0.4593rs5020531
hTAS2R42EC2 0.00Y175F0.4593rs35969491
hTAS2R42EC3 0.00Y265C0.2200rs1451772