BitterDB ID=967

Cucurbitacin D help

BitterDB id=967
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Lossow K, Hbner S, Roudnitzky N, Slack JP, Pollastro F, et al. (2016). Comprehensive Analysis of Mouse Bitter Taste Receptors Reveals Different Molecular Receptive Ranges for Orthologous Receptors in Mice and Humans. J Biol Chem 291(29): 15358-77. PubMed 27226572
[2] Glendinning JI (1994). Is the bitter rejection response always adaptive? Physiol Behav 56(6): 1217-27. PubMed 7878094

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r10 PubMed:27226572
Human  hTas2r46 PubMed:27226572

Sensory data about the compound bitterness: help

There is no sensory data available

Properties: help

516.68 [g/mol] 2.92850
4 7
0 4
4
8.21 [mg/kg B.W.]

Identifiers: help

3877-86-9
C30H44O7
SRPHMISUTWFFKJ-QJNWWGCFSA-N

Links:

[1] 5281318