BitterDB ID=942

Diclofenac help

BitterDB id=942
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Schiffman SS, Zervakis J, Westall HL, Graham BG, Metz A, et al. (None). Effect of antimicrobial and anti-inflammatory medications on the sense of taste. Physiol Behav 69(4-5): 413-24. PubMed 10913779
[2] Levit A, Nowak S, Peters M, Wiener A, Meyerhof W, et al. (2014). The bitter pill: clinical drugs that activate the human bitter taste receptor TAS2R14. FASEB J 28(3): 1181-97. PubMed 24285091 primarily bitter taste, with additional medicinal, metallic, astringent, and salty ratings for both young and elderly groups.

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r14 25 PubMed:24285091

Sensory data about the compound bitterness: help

Sensory Data Type Value Reference
Bitter recognition threshold 4 [mM] Reference

Properties: help

296.15 [g/mol] 4.36410
2 2
2 2
62.4 [mg/kg B.W.]

Identifiers: help



[1] 3033
[2] ZINC000000001281
[3] DB00586
[4] 2714