BitterDB ID=900

(+)-taxifolin, taxifoline help

BitterDB id=900
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Roland WS, van Buren L, Gruppen H, Driesse M, Gouka RJ, et al. (2013). Bitter taste receptor activation by flavonoids and isoflavonoids: modeled structural requirements for activation of hTAS2R14 and hTAS2R39. J Agric Food Chem 61(44): 10454-66. PubMed 24117141
[2] Intelmann, D. et al. Three TAS2R Bitter Taste Receptors Mediate the Psychophysical Responses to Bitter Compounds of Hops (Humulus lupulus L.) and Beer. Chemosensory Perception 2, 118-132(2009). springerlink strongly bitter

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r14 63 PubMed:24117141
Human  hTas2r39 125 PubMed:24117141

Sensory data about the compound bitterness: help

There is no sensory data available

Properties: help

304.25 [g/mol] 1.18630
5 7
2 3
1

Identifiers: help

20254-28-8,480-18-2
C15H12O7
CXQWRCVTCMQVQX-MLCCFXAWSA-N

Links:

[1] 439533
[2] ZINC000000105076 ZINC000100018343
[3] DB02224