BitterDB ID=71

Amarogentin help

BitterDB id=71 , Natural
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, et al. (2010). The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35(2): 157-70. PubMed 20022913
[2] Glendinning JI (1994). Is the bitter rejection response always adaptive? Physiol Behav 56(6): 1217-27. PubMed 7878094
[3] URL link biterness of 1:58,000,000, most bitter compound known
[4] Merck Index Monograph Number:

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r1 30 PubMed:20022913
Human  hTas2r4 300 PubMed:20022913
Human  hTas2r39 300 PubMed:20022913
Human  hTas2r43 30 PubMed:20022913
Human  hTas2r46 10 PubMed:20022913
Human  hTas2r47 3 PubMed:20022913
Human  hTas2r50 100 PubMed:20022913
Chicken  ggTas2r7 100 PubMed:25180257
Mouse  mTas2r105 0.3 4 PubMed:27226572
Mouse  mTas2r108 1000 PubMed:27226572
Mouse  mTas2r123 300 160 PubMed:27226572
Mouse  mTas2r144 1000 PubMed:27226572

Sensory data about the compound bitterness: help

Sensory Data Type Value Reference
Bitter recognition threshold 0.004 [mM] Reference
Bitter recognition threshold 0.000029 [mM] Reference

Properties: help

586.55 [g/mol] 1.05690
6 13
2 5
7

Identifiers: help

21018-84-8
C29H30O13
DBOVHQOUSDWAPQ-WTONXPSSSA-N

Links:

[1] 115149
[2] ZINC000003982136