BitterDB ID=645

Phenyl beta-D-glucopyranoside help

BitterDB id=645
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Sakurai T, Misaka T, Ishiguro M, Masuda K, Sugawara T, et al. (2010). Characterization of the beta-D-glucopyranoside binding site of the human bitter taste receptor hTAS2R16. J Biol Chem 285(36): 28373-8. PubMed 20605788
[2] Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (2002). The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides. Nat Genet 32(3): 397-401. PubMed 12379855

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r16 380 PubMed:20605788
Mouse  mTas2r119 10000 PubMed:27226572
Mouse  mTas2r125 3000 PubMed:27226572
Mouse  mTas2r126 10000 PubMed:27226572

Sensory data about the compound bitterness: help

Sensory Data Type Value Reference
Bitter recognition threshold 0.1 [mM] Reference
Bitter recognition EC50 0.7 [mM] Reference

Properties: help

256.25 [g/mol] -1.13470
4 6
1 2
3

Identifiers: help

1464-44-4
C12H16O6
NEZJDVYDSZTRFS-RMPHRYRLSA-N

Links:

[1] 65080
[2] ZINC000004096022