BitterDB ID=55

Quassin help

BitterDB id=55 , Natural
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Rodgers S, Glen RC, Bender A (None). Characterizing bitterness: identification of key structural features and development of a classification model. J Chem Inf Model 46(2): 569-76. PubMed 16562985
[2] Dotson CD, Zhang L, Xu H, Shin YK, Vigues S, et al. (2008). Bitter taste receptors influence glucose homeostasis. PLoS One 3(12): e3974. PubMed 19092995
[3] Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, et al. (2010). The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35(2): 157-70. PubMed 20022913
[4] Merck Index Monograph Number: Very bitter rectangular plates from dilute methanol

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r4 300 PubMed:20022913
Human  hTas2r10 300 PubMed:20022913
Human  hTas2r14 300 PubMed:20022913
Human  hTas2r46 300 PubMed:20022913
Human  hTas2r47 300 PubMed:20022913
Chicken  ggTas2r7 300 PubMed:25180257
Mouse  mTas2r105 300 PubMed:27226572

Sensory data about the compound bitterness: help

There is no sensory data available

Properties: help

388.46 [g/mol] 2.81900
0 6
0 4
2

Identifiers: help

76-78-8
C22H28O6
IOSXSVZRTUWBHC-LBTVDEKVSA-N

Links:

[1] 65571
[2] ZINC000003978633