BitterDB ID=53

Papaverine help

BitterDB id=53 , Natural
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, et al. (2010). The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35(2): 157-70. PubMed 20022913
[2] Guinard JX, Hong DY, Zoumas-Morse C, Budwig C, Russell GF (1994). Chemoreception and perception of the bitterness of isohumulones. Physiol Behav 56(6): 1257-63. PubMed 7878099

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r7 10 PubMed:20022913
Human  hTas2r10 10 PubMed:20022913
Human  hTas2r14 10 PubMed:20022913
Mouse  mTas2r144 10 PubMed:27226572

Sensory data about the compound bitterness: help

Sensory Data Type Value Reference
Bitter recognition threshold 0.063 [mM] Reference

Properties: help

339.39 [g/mol] 3.86000
0 5
3 3
6
325 [mg/kg B.W.]

Identifiers: help

58-74-2,61-25-6
C20H21NO4
XQYZDYMELSJDRZ-UHFFFAOYSA-N

Links:

[1] 4680
[2] ZINC000000056555
[3] DB01113