BitterDB ID=50

Cucurbitacin B help

BitterDB id=50 , Natural
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, et al. (2010). The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35(2): 157-70. PubMed 20022913
[2] Glendinning JI (1994). Is the bitter rejection response always adaptive? Physiol Behav 56(6): 1217-27. PubMed 7878094

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r10 0.01 PubMed:20022913
Human  hTas2r14 100 PubMed:20022913
Mouse  mTas2r105 30 PubMed:27226572
Mouse  mTas2r114 3 PubMed:27226572

Sensory data about the compound bitterness: help

Sensory Data Type Value Reference
Bitter recognition EC50 0.000001 [mM] Reference

Properties: help

558.71 [g/mol] 3.49930
3 8
0 4
5

Identifiers: help

C32H46O8
IXQKXEUSCPEQRD-ALLWXVAWSA-N

Links:

[1] 6433476