BitterDB ID=120

Propylthiouracil help

BitterDB id=120 , Synthetic
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Dotson CD, Zhang L, Xu H, Shin YK, Vigues S, et al. (2008). Bitter taste receptors influence glucose homeostasis. PLoS One 3(12): e3974. PubMed 19092995
[2] Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, et al. (2010). The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35(2): 157-70. PubMed 20022913
[3] Merck Index Monograph Number:

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r38 0.11 PubMed:20022913
Mouse  mTas2r105 300 PubMed:27226572
Mouse  mTas2r108 1000 PubMed:27226572
Mouse  mTas2r120 300 PubMed:27226572
Mouse  mTas2r121 300 PubMed:27226572
Mouse  mTas2r135 300 PubMed:27226572
Mouse  mTas2r137 1000 PubMed:27226572
Cat  fTas2r2 PubMed:26488302
Cat  fTas2r4 PubMed:26488302

Sensory data about the compound bitterness: help

There is no sensory data available

Properties: help

170.24 [g/mol] 1.38499
2 2
1 1
2

Identifiers: help

51-52-5
C7H10N2OS
KNAHARQHSZJURB-UHFFFAOYSA-N

Links:

[1] 657298
[2] ZINC000004640636
[3] DB00550
[4] 6650