BitterDB ID=104

Helicin help

BitterDB id=104 , Natural
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, et al. (2010). The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35(2): 157-70. PubMed 20022913
[2] Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (2002). The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides. Nat Genet 32(3): 397-401. PubMed 12379855

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r16 400 PubMed:20022913
Human  hTas2r43 1000 PubMed:20022913
Mouse  mTas2r126 10000 PubMed:27226572

Sensory data about the compound bitterness: help

Sensory Data Type Value Reference
Bitter recognition threshold 0.4 [mM] Reference
Bitter recognition EC50 2.2 [mM] Reference

Properties: help

284.26 [g/mol] -1.32220
4 7
1 2
4

Identifiers: help

618-65-5,6304-80-9
C13H16O7
BGOFCVIGEYGEOF-UJPOAAIJSA-N

Links:

[1] 101799
[2] ZINC000004027427