BitterDB ID=103

Arbutin help

BitterDB id=103 , Natural
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, et al. (2010). The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35(2): 157-70. PubMed 20022913
[2] Sakurai T, Misaka T, Ishiguro M, Masuda K, Sugawara T, et al. (2010). Characterization of the beta-D-glucopyranoside binding site of the human bitter taste receptor hTAS2R16. J Biol Chem 285(36): 28373-8. PubMed 20605788
[3] Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (2002). The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides. Nat Genet 32(3): 397-401. PubMed 12379855

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r16 700 5800 PubMed:20022913
Human  hTas2r16 1340 PubMed:20605788
Mouse  mTas2r126 30000 PubMed:27226572

Sensory data about the compound bitterness: help

Sensory Data Type Value Reference
Bitter recognition threshold 0.9 [mM] Reference
Bitter recognition EC50 5.4 [mM] Reference

Properties: help

272.25 [g/mol] -1.42910
5 7
1 2
3

Identifiers: help

2872-65-3,30373-96-7,497-76-7
C12H16O7
BJRNKVDFDLYUGJ-RMPHRYRLSA-N

Links:

[1] 440936
[2] ZINC000000518554