BitterDB ID=100

Strychnine help

BitterDB id=100 , Natural
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, et al. (2010). The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35(2): 157-70. PubMed 20022913
[2] URL link intense bitter taste
[3] Merck Index Monograph Number:

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r10 3 PubMed:20022913
Human  hTas2r10 21.8 PubMed:24266887
Human  hTas2r46 0.1 PubMed:20022913
Human  hTas2r46 0.43 PubMed:17595105
Mouse  mTas2r117 10 PubMed:27226572
Mouse  mTas2r140 10 PubMed:27226572

Sensory data about the compound bitterness: help

Sensory Data Type Value Reference
Bitter recognition threshold 0.0016 [mM] Reference

Properties: help

334.42 [g/mol] 2.09250
0 3
1 7
0
2.35 [mg/kg B.W.]

Identifiers: help

57-24-9
C21H22N2O2
QMGVPVSNSZLJIA-FVWCLLPLSA-N

Links:

[1] 441071
[2] ZINC000000119434
[3] 347