Cucurbitacin E, Cucurbitacins
BitterDB id=97 , Natural Detailed experimental validation described in the associated resource.
References for the compound bitterness
Resource
Comment
[1]
Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, et al. (2010). The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35(2): 157-70. PubMed 20022913
[2]
URL link
[3]
Cui M. et al. Activation of specific bitter taste receptors by olive oil phenolics and secoiridoids, Sci Rep, 2021, 11, 22340 PubMed 34785711
[4]
Lang T. et al. Activation Profile of TAS2R2, the 26th Human Bitter Taste Receptor, Molecular Nutrition & Food Research, 2023, 67(11) PubMed 36929150
[5]
Glendinning JI (1994). Is the bitter rejection response always adaptive? Physiol Behav 56(6): 1217-27. PubMed 7878094
[6]
Merck Index Monograph Number: 2614
Known bitter receptors targets:
Sensory data about the compound bitterness:
Sensory Data Type
Value
Reference
Bitter recognition threshold
0.000018 [mM]
Reference
Properties:
Mol. Weight: 556.7000 [g/mol] AlogP(octanol-water): 4.19020
# Hydrogen Bond Donor: 3# Hydrogen Bond Acceptor: 8
# Aromatic Rings: 0# Rings: 4
# Rotatable Bonds: 5
Identifiers:
CAS Registry Number:
18444-66-1
Formula: C32H44O8
IUPAC Systematic Name:
Show IUPAC Name
SMILES:
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Canonical SMILES:
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InChI Key: NDYMQXYDSVBNLL-OUKQBFOZSA-N
Links:
hTas2r10
mTas2r105