Dapsone help

BitterDB id=93 , Synthetic
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, et al. (2010). The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35(2): 157-70. PubMed 20022913
[2] Lang T. et al. Activation Profile of TAS2R2, the 26th Human Bitter Taste Receptor, Molecular Nutrition & Food Research, 2023, 67(11) PubMed 36929150
[3] Yang J. et al. Discovery and verification of bitter components in Panax notoginseng based on the integrated strategy of pharmacophore model, system separation and bitter tracing technology, Food Chemistry, 2023, 428, 136716 PubMed 37413835

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r4 100 PubMed:20022913
Human  hTas2r10 100 PubMed:20022913
Human  hTas2r40 30.0 PubMed:20022913

Sensory data about the compound bitterness: help

There is no sensory data available

Properties: help

248.3100 [g/mol] 1.68380
2 4
2 2
2

Identifiers: help

14548-46-0,80-08-0
C12H12N2O2S
MQJKPEGWNLWLTK-UHFFFAOYSA-N

Links:

[1] 2955
[2] ZINC000000006310
[3] DB00250