Genistin help

BitterDB id=816 , Natural
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Drewnowski A, Gomez-Carneros C (2000). Bitter taste, phytonutrients, and the consumer: a review. Am J Clin Nutr 72(6): 1424-35. PubMed 11101467 bitter and astringent
[2] URL link
[3] Roland W. S. U. et al. Soy Isoflavones and Other Isoflavonoids Activate the Human Bitter Taste Receptors hTAS2R14 and hTAS2R39, Journal of Agricultural and Food Chemistry, 2011, 59 (21), 11764-11771 PubMed 21942422
[4] Roland W. S. U. et al. Bitter Taste Receptor Activation by Flavonoids and Isoflavonoids: Modeled Structural Requirements for Activation of hTAS2R14 and hTAS2R39, J. Agric. Food Chem., 2013, 61, 44, 10454–10466 PubMed 24117141
[5] Li L. et al. A comprehensive review of the metabolism of citrus flavonoids and their binding to bitter taste receptors, Comprehensive Reviews in Food Science and Food Safety, 2023, 22(3), 1763-1793 PubMed 36871162

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r39 500.0 PubMed:21942422
Human  hTas2r39 500.0 PubMed:24117141
Human  hTas2r39 500.0 PubMed:36871162

Sensory data about the compound bitterness: help

There is no sensory data available

Properties: help

432.3800 [g/mol] 0.04990
6 10
3 4
4

Identifiers: help

167869-21-8,529-59-9
C21H20O10
ZCOLJUOHXJRHDI-CMWLGVBASA-N

Links:

[1] 5281377
[2] ZINC000004097913